Middletown, Delaware, is located south of the C&D Canal and about 25 miles north of the state's capital, Dover. This area is very accessible from Routes 1 and 301, thus making for easy commutes to nearby cities via I-95 and beach travel via routes south.

The heart of Middletown lies in the historic area found at the crossroads of E. Main Street (Rt. 299) and Broad Street. Many of the old buildings, once favorite stops by those carting goods to and from Delaware to nearby parts of Maryland, are being preserved through local efforts to maintain the small town's appeal despite recent growth. Annual festivals like the Olde-Tyme Peach Festival and the Hummer's Parade on New Year's Day help further this initiative.

Middletown has experienced rapid growth and commercialization in recent years due to the many new home construction opportunities for families. Local businesses as well as nationwide chains continue to be built to accommodate this growing community.